Gregory J. Basura, MD, PhD

Dr. Basura is a professor, surgeon-scientist in the Division of Otology/Neurotology-Skull Base Surgery in the Department of Otolaryngology-Head and Neck Surgery at the University of Pittsburgh. He is also the Director for Global Outreach for the Department. With a fifty percent research appointment he divides his time between patient care, basic science/human translational clinical research, resident/medical student teaching, administrative/committee, institutional service, student mentoring and global outreach/humanitarian efforts.
  
His clinical practice includes all aspects of otology/neurotology including hearing loss, chronic ear disease, facial nerve disorders including lateral skull base cerebrospinal fluid leaks, temporal lobe encephaloceles and skull base tumors. His clinical translational research involves investigating central auditory plasticity with hearing loss and tinnitus using innovative brain imaging involving functional near infrared spectroscopy. 

For humanitarian outreach/service he is involved in a newly established one-year dedicated otology clinical/surgical fellowship at the University of Cape Town in South Africa with fellowship director, Dr. Tashneem Harris. He also started the African Otology Society to build community in Africa to address otology and audiology needs. 

Dr. Basura received his Bachelor of Science in Zoology and Bachelor of Arts in Psychology with minors in chemistry and history from the College of Idaho. He completed his PhD in Anatomy and Cell Biology with an emphasis in neuroscience and neuroanatomy from Wayne State University of School of Medicine. He completed his MD from the University of Washington and Otolaryngology/Head and Neck Surgery residency at the University of North Carolina at Chapel Hill. He then completed a Neurotology/Lateral Skull Base Surgical fellowship at the University of Michigan and rose to the rank of Associate Professor with tenure at the University of Michigan before pursuing his current role as Professor and Global Director in the and Department of Otolaryngology/Head and Neck Surgery at the University of Pittsburgh. He is currently completing an MBA in Health Care Finance, Entrepreneurship and Leadership at Johns Hopkins University.

    Education & Training

  • Department of Otolaryngology-Head and Neck Surgery; University of Michigan, Post-Doctoral Research Fellowship
  • Department of Otolaryngology-Head and Neck Surgery; University of Michigan, Fellowship in Otology-Neurotology/Skull Base Surgery
  • University of North Carolina at Chapel Hill School of Medicine, Post-Doctoral Research Fellowship; Otolaryngology-Head and Neck Surgery
  • University of North Carolina Hospitals; University of North Carolina at Chapel Hill School of Medicine, Residency in Otolaryngology-Head and Neck Surgery
  • University of North Carolina Hospitals; University of North Carolina at Chapel Hill School of Medicine, Internship/Preliminary General Surgery
  • Wayne State University School of Medicine Department of Anatomy and Cell Biology, Postdoctoral Research Fellowship/Research Associate
  • Johns Hopkins University; Carey School of Business; Part-Time Flex Online Program, MBA (Health Care Management Innovation and Technology, Entrepreneurship Innovation and Technology, and Public and Private Sector Leadership sub-emphases), 2021-Present
  • University of Washington, MD
  • Wayne State University School of Medicine, PhD in Anatomy and Cell Biology/Neuroscience
  • The College of Idaho, BS in Zoology and BA in Psychology
Recent Publications

Changing Management of Intravestibular Schwannomas in the Era of Cochlear Implantation for Single-Sided Deafness. Hershey E, Chionis L, Kazemi R, Valenzuela C, El-Kashlan HK, Basura GJ, Stucken EZ. Otol Neurotol. 2024 Apr 1;45(4):e337-e341. doi: 10.1097/MAO.0000000000004140. Epub 2024 Feb 15.

Role of the otologist/neurotologist in managing auricular and periauricular cutaneous malignancies: A 10-year otologic oncology experience. Patel TR, Prince ADP, Benjamin WJ, Basura GJ. Laryngoscope Investig Otolaryngol. 2023 Oct 17;8(6):1637-1647. doi: 10.1002/lio2.1171. eCollection 2023 Dec.

Paragangliomas of the head and neck: a contemporary review. Graham NJ, Smith JD, Else T, Basura GJ. Endocr Oncol. 2022 Nov 10;2(1):R153-R162. doi: 10.1530/EO-22-0080. eCollection 2022 Jan.

Reversing Synchronized Brain Circuits Using Targeted Auditory-Somatosensory Stimulation to Treat Phantom Percepts: A Randomized Clinical Trial. Jones GR, Martel DT, Riffle TL, Errickson J, Souter JR, Basura GJ, Stucken E, Schvartz-Leyzac KC, Shore SE. JAMA Netw Open. 2023 Jun 1;6(6):e2315914. doi: 10.1001/jamanetworkopen.2023.15914.

Targeted molecular characterization of external auditory canal squamous cell carcinomas. Basura GJ, Smith JD, Ellsperman S, Bhangale A, Brenner JC. Laryngoscope Investig Otolaryngol. 2021 Sep 13;6(5):1151-1157. doi: 10.1002/lio2.654. eCollection 2021 Oct.

Full list of publications

Research Interests

Animal
•    Role of multi-sensory integration and neuro modulation in primary auditory cortex (A1) neuron plasticity following single-sided-deafness and noise-induced tinnitus
•    Neurotransmitter receptor expression in A1 in noise-induced tinnitus and following single-sided deafness (e.g., radio-ligand binding)
•    Development of animal models of single-sided deafness to mimic the human condition (e.g., diphtheria toxin receptor model)

Human
•    Human translational studies using functional near-infrared spectroscopy (fNIRS) to investigate central auditory pathways in unilateral sudden hearing loss and tinnitus
•    Adaptations of fNIRS probes to the external ear canal to increase brain neuroimaging surveillance capacity
•    Human studies are conducted in conjunction with ongoing basic science listed above to better characterize central auditory plasticity and potential objectify measurable neural correlates of tinnitus
•    Developing data base for patient prevalence and outcomes in single-sided deafness
•    Classifying genetics and prevalence of head and neck neuroendocrine tumors
•    Clinical presentation and management of peri-auricular and temporal bone cutaneous malignancies
•    Pediatric hearing loss in peri-urban communities of Kumasi, Ghana
•    Developing objectified metrics to gauge clinical and surgical skills acquisition in medical trainees in Kumasi, Ghana (Komfo Anokye Teaching Hospital; KATH-UM partnership)
•    Had Developed otology fellowship in Alexandria, Egypt for African physicians to obtain dedicated one-year surgical training in otology prior to returning to their home Country (fellowship cancelled due to COVID-19 pandemic)
•    Helped to develop and initiate the first dedicated otology surgical fellowship on Africa at the University of Cape Town (UCT) South Africa. MedEl sponsored one-year otology fellowship. Serving as an adjunctive instructor giving weekly virtual/on-line zoom lectures to residents and fellows and two site visits to UCT per year (3/2022-present)
•    Launched the African Otological Society (www.afotos.org) November 2023

Research Grants

Subjective and Somatic Tinnitus: Using Functional Near-Infrared-Spectroscopy to Identify Objective Correlates in Auditory and Non-Auditory Cortices; National Institutes of Health 1R01 DC021746-01; NIDCD; University of Pittsburgh     PI: Basura, Gregory; MD, PhD; Funded 9/1/2024-6/30/2029